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Methotrexate

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Methotrexate is a medication used in the treatment of various types of cancer and autoimmune diseases. It works by inhibiting the metabolism of folic acid, which is necessary for cell growth and replication. This action helps to control the rapid proliferation of abnormal cells in conditions like cancer and to suppress the immune system in diseases where it attacks the body's own tissues.

How is this medication used?

The administration of methotrexate can vary, depending on the condition being treated. It is available in tablet form, as an injectable, and in a solution that can be taken by mouth. It's important to follow your healthcare provider's instructions closely regarding how to take this medication. This might include taking the medication on a specific day of the week and following dietary restrictions. Regular monitoring through blood tests is required to adjust dosages and to monitor for adverse effects.

What are the possible side effects?

Common side effects of methotrexate include nausea, vomiting, loss of appetite, and fatigue. It can also lead to more serious side effects such as liver damage, kidney damage, lung disease, and a decrease in blood cells that can cause infections, anemia, or easy bruising. Because of its potential to cause fetal harm, it is not recommended for use during pregnancy.

What are the potential interactions?

Methotrexate can interact with various other medications and substances. Examples include nonsteroidal anti-inflammatory drugs (NSAIDs), certain antibiotics like trimethoprim, and alcohol. These interactions can increase the risk of side effects or reduce the effectiveness of methotrexate. It's important to inform all healthcare providers of all medications you are taking to avoid potential interactions.

Disclaimer: The information provided on this website is for informational purposes only and is not intended as medical advice. Always consult with your healthcare provider for medical advice, diagnosis, or treatment. Images are for representation purposes only and actual packing may differ by brand and/or manufacturer.