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Pirfenidone

Generic alternative to Esbriet

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Pirfenidone is a medication used for the treatment of idiopathic pulmonary fibrosis (IPF). It works by reducing lung fibrosis through a reduction of the production of growth factors and inflammatory substances that drive the fibrotic process.

How is this medication used?

Pirfenidone is typically taken orally with food to minimize gastrointestinal side effects. The recommended starting dosage is one 267 mg tablet three times a day, which may be increased to a maximum of three 267 mg tablets three times a day. Patients should follow their doctor's instructions carefully regarding dosage adjustments.

What are the possible side effects?

Common side effects of pirfenidone include nausea, rash, abdominal pain, fatigue, dyspepsia, anorexia, liver enzyme elevation, and photosensitivity. It is important to contact a healthcare provider if severe side effects occur.

What are the potential interactions?

Pirfenidone can interact with other medications such as fluvoxamine, certain antibiotics (e.g., enoxacin), and CYP1A2 inhibitors, which can increase the levels of pirfenidone in the blood. Also, smokers may have decreased levels of pirfenidone compared to non-smokers. Patients should inform their healthcare provider about all the medications they are taking to avoid potential interactions.

Disclaimer: The information provided on this website is for informational purposes only and is not intended as medical advice. Always consult with your healthcare provider for medical advice, diagnosis, or treatment. Images are for representation purposes only and actual packing may differ by brand and/or manufacturer.