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Roflumilast

Generic alternative to Daliresp

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Roflumilast is an oral medication used primarily to prevent exacerbations in severe Chronic Obstructive Pulmonary Disease (COPD) associated with chronic bronchitis. It works by inhibiting phosphodiesterase-4 (PDE4), a type of enzyme that contributes to inflammation in the lungs, thus helping to reduce flare-ups.

How is this medication used?

Roflumilast is typically prescribed as a once-daily tablet, to be taken with or without food. The dosage and treatment duration depend on the patient's medical condition and response to treatment. It's important not to chew, crush, or split the tablet.

What are the possible side effects?

Common side effects of roflumilast include diarrhea, weight loss, nausea, headache, back pain, dizziness, decreased appetite, and insomnia. Serious side effects may include psychiatric symptoms such as depression and suicidality, as well as severe allergic reactions. If you experience any severe side effects, contact your doctor immediately.

What are the potential interactions?

Roflumilast can interact with certain medications, including rifampicin, phenobarbital, carbamazepine, and phenytoin, which may decrease its effectiveness. It can also have increased side effects when combined with certain antidepressants and CYP3A4 and CYP1A2 inhibitors such as erythromycin and fluvoxamine. Always inform your healthcare provider about all the medications and supplements you are taking to avoid potential interactions.

Disclaimer: The information provided on this website is for informational purposes only and is not intended as medical advice. Always consult with your healthcare provider for medical advice, diagnosis, or treatment. Images are for representation purposes only and actual packing may differ by brand and/or manufacturer.