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Tacrolimus

Generic alternative to Prograf

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Tacrolimus is an immunosuppressive medication used mainly after allogeneic organ transplant to lower the risk of organ rejection. It operates by inhibiting the activity of calcineurin, leading to a decrease in the production of inflammatory cytokines by T-cells.

How is this medication used?

Tacrolimus is generally administered orally or intravenously. The dosage and administration depend on the patient's condition, the type of organ transplanted, and body weight. It is crucial to follow the prescribing physician's directions carefully and to have blood levels of the medication monitored regularly to avoid toxicity or rejection.

What are the possible side effects?

Common side effects of tacrolimus include increased risk of infections, high blood pressure, kidney problems, tremors, headaches, and an increased risk of diabetes. Long-term use can lead to other significant adverse effects, such as an increased risk of skin cancer and lymphoma.

What are the potential interactions?

Tacrolimus can interact with a wide range of drugs including antifungal medications, antibiotics, calcium channel blockers, and anticonvulsants, which can either increase or decrease tacrolimus blood levels. Consumption of grapefruit or grapefruit juice should be avoided as it can significantly increase blood levels of the medication.

Disclaimer: The information provided on this website is for informational purposes only and is not intended as medical advice. Always consult with your healthcare provider for medical advice, diagnosis, or treatment. Images are for representation purposes only and actual packing may differ by brand and/or manufacturer.